Working to Address Liver and Cardiometabolic Diseases with Growing Needs

We are a clinical-stage biopharmaceutical company dedicated to developing and delivering innovative therapies to treat patients with liver and cardiometabolic diseases. We are driven to help change the dynamic for patients, and through our experience, know that science is key to breaking this cycle of suboptimal treatments.

Our lead candidate, pegozafermin, is an investigational glycopegylated FGF21 analog currently being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) and severe hypertriglyceridemia (SHTG). We believe that targeting FGF21, a metabolic hormone that regulates energy expenditure and glucose and lipid metabolism, may be a promising option for people with liver and cardiometabolic diseases, such as MASH and SHTG.